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Grape Seed Extract: Top Benefits and Uses (2022 Guide)

For centuries, grapes, or vitis vinifera, have been hailed for their medicinal uses and benefits. The Egyptians of 6,000 years ago included grapes as part of their diet. Ancient Greek philosophers even praised the fruit for its healing power.

In Europe, grapes have been used as traditional treatment for eye and skin diseases. Folk healers have been known to create ointments out of grapevine saps to cure infections. Today, the fruits, along with the seeds, leaves and sap, are used to remedy a wide range of health problems.

Grapes are native to Asia, but were later shipped to Europe and North America. They are fruiting berries of the genus Vitis. Their leaves are large and jagged and the fruits range in color from red, purple, and green.

General Medicinal Uses of the Grape Vine

Health Benefits of Grape Seed Extract - Grape vineThe antioxidant effects of grapes come from the substance flavonoid, which is known for lowering bad cholesterol. The specific antioxidant compound in grapeseed extract is called oligomeric proanthocyanidin (OPC).

Antioxidants destroy free radicals that cause damage to the DNA. Red grapes contain the most antioxidants compared to the purple and white varieties.

The phenolic substances in grape seed extract are very antiviral and antibacterial.

Grape leaves, on the other hand, are used for heavy menstrual bleeding and canker sores. They have astringent effects and can reduce inflammation.

Grape seeds are byproducts of wine manufacturing. Ground-up red wine seeds are commonly bought from wineries for their extracts. Although fairly new to the US market, grape seed extracts have quickly become popular dietary supplements to many, either in liquid, tablet, or capsule form. Grape seed oil is highly concentrated in Vitamin E and linoleic acid.

Health Benefits of Grape Seed Extract

Health Benefits of Grape Seed Extract - Man receiving wound careA great deal of research on the therapeutic properties of grape seed extract has been conducted over the years.

Primary benefits include treating poor circulation, healing wounds and nerve damage. Other holistic health uses encompass:

Some studies also point out the positive effect of grape seed extract to complications brought by blood disorders. They have also found that it may prevent growth of disease cells and reduce the risk of developing disease of the breast, lung, and prostate. It is also sometimes suggested for treating Alzheimer’s disease and hemorrhoids, improving night vision and combating aging.

As more scientific studies and clinical trials are being done we’re beginning to send benefits that extend to testosterone enhancement, weight loss, hair loss and more. The reviews are pretty amazing.

Health Benefits of Grape Seed Extract - Grape seed oil and grapesAlthough the FDA has not yet evaluated grape seed extract for safety and effectiveness, a lot of people have testified to its healing properties. From being a powerful antioxidant, to supplemental cure for heart problems including diastolic heart failure, blood disorders, and disease, the benefits from grapes could fill a long list.

There is growing evidence of its efficacy for weight loss and skin.

Follow dosage information on the liquid tea or tincture or dried extract powder capsules product label. You can find herbal supplements and essential oil at Walmart, Amazon, GNC, Vitamin Shoppe, etc. Please do more research to understand potential side effects and contraindications.

Is grape seed extract and resveratrol the same thing?

No. While they both come from grapes, resveratrol comes specifically from the skins of grapes used to make red wines. And while both components have similar activity in the body, they are different and have different medicinal uses and benefits.

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5 thoughts on “Grape Seed Extract: Top Benefits and Uses (2022 Guide)”

  1. Does anyone know what the shelf life of grapeseed oil is? I have read

    wildly varying estimates, from 3 months to 2 years. Of course I know

    that storage makes a big difference–I’m speaking of room temperature in

    moderate climates, refrigeration in the heat of the summer.



    • 1. you can’t get grapeseed oil organically grown

      2. you can’t get grapeseed oil cold-pressed

      3. grapeseed oil doesn’t contain any vitamin E to speak of. (Vit. E slows rancidity).

      For me, two five-liter jars have gone rancid less than half a year after I

      bought’em, fairly fresh – same year’s harvest.

      That’s two jars too many, and I no longer use grapeseed oil – especially as

      using grapeseed oil in salves means these salves won’t last as long as ones made

      from better oils.

      So it’s better to use sesame or safflower oils, which are available both

      organically grown and cold-pressed, and which contain loads of vitamin E.

      If, however, you’re using grapeseed oil as a massage oil, sure, go ahead —

      until it turns rancid, that is. Grapeseed oil is very light – it’s absorbed into

      the skin just as fast as sesame and safflower oil are.


      • Thanks, Henriette. I used to use grapeseed in salves, and it was so astonishingly

        non-greasy that I was thinking about trying it again. I never used to keep anything

        around long enough for it to get rancid. Now I’d like to make some larger

        quantities, though.

        So you are implying that sesame and safflower are as non-greasy as grapeseed? I’ve

        never used either. I have been using fractionated coconut oil, which has a very

        long shelf life. I’ve also used jojoba, which is lovely but very expensive. If

        either sesame or safflower was as light as grapeseed, I’d definitely use it.


      • I have bought organically grown, cold pressed grapeseed oil from a company

        local to me. I am in California wine country so it should come as no

        surprise that such things are available *here*. However, I did a cursory

        check on the ‘net and found other vendors of such.

        As to the Vitamin E, what did you mean by that?

        Oil Alpha-Tocopherol, mg per 100 gram sample

        Sesame 1.4

        Grapeseed 28.8

        Safflower, linoleic over 70% 34.1

        Safflower, oleic over 70% 34.

        So, grapeseed has quite a bit, a lot more than sesame! Were you referring

        to a different tocopherol or perhaps one of the tocotrienols?

  2. Would there be a difference in shelf life between food-grade and cosmetic-grade

    grapeseed oil? I have Frontier grapeseed oil, labeled “aromatherapy”, “for

    cosmetic use only”, for use as a carrier oil with aromatherapy essential oils.

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